An unambiguous paper-based test for malaria
Current colorimetric rapid tests for malaria can be difficult to interpret correctly when protein biomarkers are present in blood at low abundances. We have produced prototype tests for malaria caused by Plasmodium falciparum that exhibit enhanced thermal stability and unambiguous colorimetric readouts in comparison with existing tests. We will conduct validation studies using clinical samples, including side-by-side testing with gold standard, PCR-based methods. We will also extend the concept to produce tests that diagnose malaria caused by P. vivax and P. knowlesi.