Monitoring artemisinin resistance in malaria via functional measurements
Artemisinin-resistant malaria parasites, which emerged within the last decade in Southeast Asia, threaten the efficacy of the current standard of care for malaria. Conventional methods to detect artemisinin-resistant parasites are either too time-consuming or with limited specificity, or both. Previous MIT-NTU collaboration on malaria parasite detection and resistance generated many promising, functionally-relevant modalities of detecting parasite resistance early (within 24 hours), in order to provide actionable information for better clinical management.
In this project, we will continue developing these technologies, with the goal of implementing a system that are readily deployable on the field, with minimal needs for research and manpower infrastructures.